Not all Protein is Created Equal

It is widely known that the human body needs 20 amino acids (the building blocks of protein), nine of which are considered essential and need to be obtained through diet. A “complete” protein would be one that contains all nine essential amino acids; this includes phenylalanine, valine, tryptophan, threonine, isoleucine, methionine, histidine, leucine, and lysine. The protein profile of food is generalized to total protein content and much less often to amino acid content. What we rarely hear about is how much of each amino acid we need and how to obtain each one.

Methionine, an essential amino acid, has been studied over the years for its effect on chronic disease development and longevity. Specifically, a low methionine diet has been associated with a longer lifespan (1). The reason for this is that methionine may induce oxidative stress, which can negatively impact aging and metabolic processes, leading to problems like obesity and diabetes (1). Interestingly, the types of foods that typically contain high levels of methionine have been associated with chronic disease in multiple other studies. As a plant-based nutritionist, I am particularly interested when finding a connection between plant-based nutrition and longevity.

According to this nutrient search tool, foods highest in methionine are primarily animal-based foods, including chicken, turkey, lamb, steak, pork, tuna, and other fish. The highest plant-based source of methionine is firm tofu, ranking 154th on the list (2). Perhaps, the issue is not methionine itself but the “antinutrients” contained in animal products that associate methionine to chronic disease and premature death. Meat, poultry, and fish products contain cholesterol and saturated fats, whereas plant-based foods are cholesterol-free and tend to be low in saturated fats.

It is true that, in most cases, animal-based foods contain more protein than plant-based foods, and it is much easier to obtain protein by eating meat, poultry, and fish. The real question is, does higher protein necessarily mean higher quality? All in all, it seems that animal-based products are a higher risk for disease development. The more time I spend analyzing research findings, the more I find that a balanced plant-based diet is the best diet for longevity.